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Gadolinium dosing module.

a) SCMR official document standardized acquisition guidelines – relevant extract

1. Volumes and injection rates depend on scan duration:the given values are recommendations for typical scan times.
2. Injection rates are different for 1 molar contrast agents. As a general rule, divide the given injection rates by a factor of 2.
3. Contrast agents with higher relaxivity (e.g., gadobenate dimeglumine) require smaller doses.
4. Throughout the protocols, the term "gadolinium" refers to gadolinium chelates
5. Injection rate for peripheral angiography with ellipticcentric readouts may be different than those specified below.
   

Table 1: Contrast and chasing bolus doses and injection rates

 

b) SCMR official document reporting recommendations – relevant extract

History and Risk Factors (2 recommended and 1 optional element)
For studies using contrast, the SCMR suggests the value and date of acquisition of the most
recent serum creatinine level and estimated glomerular filtration rate (GFR) should be
provided.

Non-imaging findings associated with the examination (5 recommended elements)
For studies utilizing contrast agents, the type (i.e. paramagnetic), name, route, site, and
speed of administration should be provided.

c) Relevant Online Talks

Free talks

The Scientific background behind medicolegal aspects of gadolinium and NSF
By Martin R Prince - Cornell and Columbia Universities
Recorded at Scmr 2010

Hyperpolarized CM
By Damian Tyler
Recorded at EuroCMR 2008

Blood Pool CM
By Massimo Lombardi
Recorded at EuroCMR 2008

Conventional Gd-Chelates: NSF
By Georg Bongartz
Recorded at EuroCMR 2008

Members only talks - general

Contrast-enhanced Sequences
By Tom Foo - GE, Schenectady
Recorded at SCMR2008 Physician Pre-Conference Section 1: MR Physics

Members only talks - cutting edge

Low Dose Gadolinium MRA
By J Paul Finn - David Geffen School of Medicine at UCLA
Recorded at SCMR 2009 Nephrogenic Systemic Fibrosis Era - Contrast enhanced vs Non-contrast enhanced

NSF - Is this an overblown risk?
By Brett Elicker - UCSF Medical Centre
Recorded at SCMR 2009 Nephrogenic Systemic Fibrosis Era - Contrast enhanced vs Non-contrast enhanced

Non-contrast MRA - Abdominal Aora, Renal Arteries and Peripheral
By Robert Edelman - Evanston Hospital
Recorded at SCMR 2009 Nephrogenic Systemic Fibrosis Era - Contrast enhanced vs Non-contrast enhanced

Time Resolved Contrast-Enhanced MRA
By James Carr - Northwestern Memorial Hospital
Recorded at SCMR 2009 Nephrogenic Systemic Fibrosis Era - Contrast enhanced vs Non-contrast enhanced

d) Relevant papers

Andreas Kribben, Oliver Witzke, Uwe Hillen, Jörg Barkhausen, Anton E. Daul, and Raimund Erbel
Nephrogenic Systemic Fibrosis: Pathogenesis, Diagnosis, and Therapy
J Am Coll Cardiol 2009 53: 1621-1628