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Number 07-07: HCM with LVOT obstruction by CMR
Karen Smith, Carsten Schmalfuss, Roger Shifrin, Norbert Wilke, Gary
Cooper, Departments of Radiology and Medicine, University of Florida, Gainesville,
Florida, USA.
Clinical: 62 year old man with HCM with obstruction referred
for alcohol septal ablation (ASA) refractory symptoms of angina and dyspnea.
This was a baseline study done prior to ASA.,
Examination: Harsh apical 3/6 holosystolic murmur, accentuated
with Valsalva maneuver.
CMR: Asymmetric septal hypertrophy, systolic anterior motion
of the anterior leaflet of the mitral valve and moderate mitral regurgiation.
No resting perfusion defect or late gadolinium enhancement.
Echo: Complements the CMR and shows high frequency events
(aortic valve fluttering and premature closure) and the SAM. Resting gradient
was 52mmHg, 104 with provocation.
Perspective: CMR can follow the effect of ASA in reducing
ASH, localizing the MI, and tracking changes in the LV, LVOTO and MR.
Scanner: Siemens Sonata 1.5T
Reference: Valeti
et al. JACC 2007;49:350-7.
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